Endogenous glutamatergic inputs to the Parabrachial Nucleus/Kölliker-Fuse Complex determine respiratory rate
نویسندگان
چکیده
منابع مشابه
Hypoplasia of the parabrachial/kölliker-fuse complex in perinatal death.
We report the first observation of perinatal death attributable to morphological alterations of the parabrachial/Kölliker-Fuse complex. In an infant, born at 41 weeks of gestation with severe signs of asphyxia and dead 20 h after delivery, we observed the presence of rare and immature neurons in the brain stem areas of both lateral and medial parabrachial nuclei and the absence of the character...
متن کاملCytoarchitectural organization of the parabrachial/Kölliker-Fuse complex in man.
While the parabrachial/Kölliker-Fuse complex has been described in a variety of animal species it has not been characterized in human brainstem. In the present study we investigated fetal and infant brainstems, focusing particularly on the dorsolateral part of the pontine tegmentum, with the aim of defining the precise cytoarchitecture of the medial parabrachial, lateral parabrachial, and Kölli...
متن کاملDopamine selects glutamatergic inputs to neostriatal neurons.
Glutamatergic synaptic potentials induced by micromolar concentrations of the potassium conductance blocker 4-aminopyridine (4-AP) were recorded intracellularly from rat neostriatal neurons in the presence of 10 microM bicuculline (BIC). These synaptic potentials originate from neostriatal cortical and thalamic afferents and were completely blocked by 10 microM 6-cyano-7-nitroquinoxaline-2,3-di...
متن کاملRegulation of the Caudal Ventrolateral Medulla by Glutamatergic and Respiratory - Related Inputs
GABAergic neurons in the caudal ventrolateral medulla (CVLM) are driven by baroreceptor inputs relayed via the nucleus tractus solitarius (NTS), and they inhibit neurons in rostral ventrolateral medulla to reduce SNA and AP. After arterial baroreceptor denervation or lesions of the NTS, inhibition of the CVLM continues to increase AP, suggesting additional inputs also tonically activate the CVL...
متن کاملResponses of primate caudal parabrachial nucleus and Kölliker-fuse nucleus neurons to whole body rotation.
The caudal aspect of the parabrachial (PBN) and Kölliker-Fuse (KF) nuclei receive vestibular nuclear and visceral afferent information and are connected reciprocally with the spinal cord, hypothalamus, amygdala, and limbic cortex. Hence, they may be important sites of vestibulo-visceral integration, particularly for the development of affective responses to gravitoinertial challenges. Extracell...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Respiratory Physiology & Neurobiology
سال: 2020
ISSN: 1569-9048
DOI: 10.1016/j.resp.2020.103401